Mangosteen pericarp

Posted: February 12, 2012 in MANAJEMEN, Obat herbal

mangosteen pericarp contain
– two new highly oxygenated prenylated xanthones, 8-hydroxycudraxanthone G (1)
– and mangostingone [7-methoxy-2-(3-methyl-2-butenyl)-8-(3-methyl-2-oxo-3-butenyl)-1,3,6-trihydroxyxanthone, 2],
– together with 12 known xanthones, cudraxanthone G (3),
– 8-deoxygartanin (4)
– garcimangosone B (5)
– garcinone D (6)
– garcinone E (7)
– gartanin (8)
– 1-isomangostin (9)
– α-mangostin (10), γ-mangostin (11), mangostinone (12)
– smeathxanthone A (13), and tovophyllin A (14).

Compounds 1, 8, 10, 11, and 13 were the most active.

Reference: J. Agric. Food Chem., 2006, 54 (6), pp 2077–2082
DOI: 10.1021/jf052649z

Known Benefits of Xanthones below:

Scientific research has made it abundantly clear that no other fruit compares in its health benefits to mangosteen, due to its xanthones and other nutritional properties.

Helping to fight cancer is just one of the many properties that different xanthones perform. For instance, one study performed in Japan showed that the xanthone alpha-mangostin had apparent properties that suppressed the development of tumors. Another, performed in China, found the xanthone garcinone E to show significant anticancer effects in terms of liver, lung, and gastric cancer cells.

In addition, some xanthones have shown significant antimicrobial effects in terms of fighting MRSA (methicillin-resistant staphylococcus aureus), which is a bacterial strain known for its tenacious resistance to pharmacologic antibiotics. One scientific study also showed that alpha-mangostin, beta-mangostin, and garcinone B to have pronounced inhibition effects on a strain of tuberculosis.

As if that isn’t enough, xanthones have also been scientifically proven to help lower LDL, the bad cholesterol, by protecting the LDL from coming into contact with free radicals, thus leaving it unable to oxidize and attach to arterial walls and cause atherosclerosis.

Taking into account the anticancer, antiinflammatory, antimicrobial, and cholesterol-lowering effects of the xanthones found in mangosteen, here is just a sampling of the other many benefits that science has either researched or is in the process of discovering:

-Helps lower blood pressure
-Helps fight fatigue
-Prevents stomach ulcers
-Aids with weight loss
-Combats diarrhea
-Pain reducer
-Heart protective
-Anti-parkinsonian and anti-Alzheimer
-Lowers fevers
-Builds immunity to disease

Indeed, even now some health practitioners are suggesting drinking mangosteen juice for relief to people who suffer from the following diseases:
-Skin ailments like psoriasis, seborrhea, or eczema
-Joint problems and arthritis
-Anxiety and depression
-Chronic pain
-Chronic fatigue syndrome

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